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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CBFA2T3 All Species: 15.76
Human Site: T154 Identified Species: 38.52
UniProt: O75081 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75081 NP_005178.4 653 71192 T154 G F S N G P A T S S T A S L S
Chimpanzee Pan troglodytes XP_001138672 657 71189 T154 G F S N G P A T S S T A S L S
Rhesus Macaque Macaca mulatta XP_001090215 652 70879 T154 G F S N G P A T S S T A S L S
Dog Lupus familis XP_546780 666 73220 T167 G F S N G P A T S S T A S L S
Cat Felis silvestris
Mouse Mus musculus O54972 620 68014 L149 P A C G A R Q L S K L K R F L
Rat Rattus norvegicus NP_001101923 619 67905 S149 A C G A R Q L S K L K R F L T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505430 605 67678 R149 P E I G E R V R T L V L G L V
Chicken Gallus gallus Q5F3B1 591 64855 G146 R V R T L V L G L V N S T L T
Frog Xenopus laevis Q9IAB2 586 65036 T141 V L A L V N S T V T I E E F H
Zebra Danio Brachydanio rerio XP_686984 647 71175 R152 P E I G E R V R S L V L G L V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 93.3 95.7 81.8 N.A. 84.9 84.5 N.A. 67 75.6 53.7 70.2 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 94.8 96.4 85.2 N.A. 89.1 88.3 N.A. 77.3 81.4 66.6 78.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 6.6 6.6 N.A. 6.6 6.6 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 6.6 20 N.A. 13.3 26.6 26.6 13.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 10 10 10 0 40 0 0 0 0 40 0 0 0 % A
% Cys: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 20 0 0 20 0 0 0 0 0 0 10 10 0 0 % E
% Phe: 0 40 0 0 0 0 0 0 0 0 0 0 10 20 0 % F
% Gly: 40 0 10 30 40 0 0 10 0 0 0 0 20 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 0 20 0 0 0 0 0 0 0 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 10 10 10 0 0 0 % K
% Leu: 0 10 0 10 10 0 20 10 10 30 10 20 0 80 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 40 0 10 0 0 0 0 10 0 0 0 0 % N
% Pro: 30 0 0 0 0 40 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 10 0 10 30 0 20 0 0 0 10 10 0 0 % R
% Ser: 0 0 40 0 0 0 10 10 60 40 0 10 40 0 40 % S
% Thr: 0 0 0 10 0 0 0 50 10 10 40 0 10 0 20 % T
% Val: 10 10 0 0 10 10 20 0 10 10 20 0 0 0 20 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _